No Stomach for Cancer | Be Strong Hearted

A Network for Gastric Cancer Patients, Survivors and Families

Be Strong Hearted ®

Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research

Posted by Karen Chelcun Schreiber On July - 20 - 2010

An article published recently in the Journal of Medical Genetics outlines new recommendations for management of patients and families with Hereditary Diffuse Gastric Cancer, based on a workshop of the International Gastric Cancer Linkage Consortium (IGCLC) held in late 2008.  The workshop, convened in Cambridge, UK, included expert geneticists, gastroenterologists, oncologists, surgeons, and pathologists from nine countries, and discussion topics included genetic counselling and testing, surveillance endoscopy, prophylactic gastrectomy, and review of pathology specimens.

Some of the outcomes of the IGCLC workshop include: Read the rest of this entry »

Education, Front, Gastrectomy, Genetics, HDGC, Hereditary Diffuse Gastric Cancer, Lobular Breast Cancer, Research

The Doctors TV: Desperate To Save A Life

Posted by Karen Chelcun Schreiber On March - 15 - 2010

The Doctors TV aired a program on Monday, February 1 titled Desperate To Save A Life. It includes a segment about Hereditary Diffuse Gastric Cancer (HDGC).  If only one at risk family is identified, if only one life saved …

View the two part segment:

Desperate To Save A Life, Part One

Desperate To Save A Life, Part Two

Front

A story of hope: Elizabeth Lambert shares her family story

Posted by Karen Chelcun Schreiber On March - 11 - 2010

Elizabeth Lambert, a teacher and a member of the Board of Directors of No Stomach For Cancer, Inc., is dedicated to raising awareness and educating the public about diffuse stomach cancer.  Like many others, her family has been affected by a hereditary form of stomach cancer. 

Elizabeth’s family was featured in a January 22, 2010 episode of Chronicle about genetics which aired on WCVB Boston Channel 5 on January 22, 2010.  View the Walsh Family Stomach Cancer video on You Tube.

A story of hope: Family has stomachs removed to fight cancer, an article written by Aaron Nicodemus, appeared in the Worcester Telegram and Gazette, Worcester, MA on February 2, 2010.

Families, Genetics, News

Hereditary Diffuse Gastric Cancer (HDGC)

Posted by Karen Chelcun Schreiber On January - 29 - 2010

Gastric cancer is the second most common cause of cancer-related death in the world.

The American Cancer Society estimated that 21,500 new cases of stomach (gastric) cancer would be diagnosed in the United States in 2008.1 Because gastric cancer is difficult to diagnose, it is often discovered in patients at a late stage with a poor prognosis. The treatment for gastric cancer is surgery and chemotherapy;2 however, the overall 5-year survival rate is low, at 24.3%.1

It is estimated that 1-3% of cases of gastric cancer are caused by Hereditary Diffuse Gastric Cancer.2 Hereditary diffuse gastric cancer (HDGC) is an inherited cancer syndrome that leads to an increased risk for both diffuse gastric cancer and lobular breast cancer in women. Patients who inherit the genetic mutation for HDGC are at high risk for developing gastric cancer at a young age.3 Read the rest of this entry »

Education, Front, Genetics, HDGC, Hereditary Diffuse Gastric Cancer, Lobular Breast Cancer

Surviving Stomach Cancer

Posted by Karen Chelcun Schreiber On January - 13 - 2010

earlyshowWORKING TO RAISE AWARENESS CHELCUN FAMILY MEMBERS APPEAR IN CBS SEGMENT ABOUT HDGC

The Chelcun family was featured in a CBS video segment with the goal of raising awareness of Hereditary Diffuse Gastric Cancer syndrome (HDGC).  While it appears to be a story about the Chelcun family, the underlying story is that of families all throughout the world. Change the family name, the family size, the individuals, the city, the country, but the story remains the same.

You may view the video, titled Surviving Stomach Cancer, currently available on You Tube.

Awareness is critical. Lives can be saved. Be an educator by sharing this with others.

Front, News

“Top Medical Advances of the Decade” include mapping the human genome; CDH1 gene mutation is example

Posted by Karen Chelcun Schreiber On December - 30 - 2009

Watch the video about Mapping the Human Genome and Stomach Cancer.

“Good Morning America” considers the discovery of genetic markers such as the one causing HDGC to be one of the top medical advances of the decade. Stomach cancer is mentioned specifically in this video from December 29, 2009 featuring Dr. Tim Johnson’s descriptions of medical breakthroughs. We are confident that the efforts of all of us impacted by HDGC and other diffuse gastric cancers, have already resulted in this national coverage: one small step in educating the world, on our journey to prevent gastric cancer and ultimately to find a cure!

Education, Front, Genetics, HDGC, Hereditary Diffuse Gastric Cancer

HDGC Research: In pursuit of stomach cancer prevention

Posted by Karen Chelcun Schreiber On November - 11 - 2009

A  prestigious James Cook Fellowship has been awarded to researcher Parry Guilford, University of Otazo, New Zealand, to pursue innovative research aimed at reversing or preventing the very early stages of stomach cancer.

Read Parry Guilford’s personal post detailing his exciting research plan for HDGC / CDH1 gene research.  His two year fellowship will begin in March, 2010.

 

The University of Otago announces Parry Guilford’s exciting award for  stomach cancer research.

More information about The Royal Society of New Zealand James Cook Research Fellowships.

Front, Genetics, HDGC, Hereditary Diffuse Gastric Cancer, Research

CDH1 gene mutation causes stomach cancer: How is it inherited?

Posted by Karen Chelcun Schreiber On November - 7 - 2009

CDH1 Mutations and Inheritance

By Amy Stettner, MS, CGC
Genetic Counselor
Madison, WI

Our bodies are made up of trillions of tiny cells. We have skin cells, muscle cells, bone cells, stomach cells, etc. Each cell contains a copy of our genetic code. This genetic code is made up of DNA and is packaged into structures called chromosomes. Read the rest of this entry »

Education, Front, Genetics, HDGC, Hereditary Diffuse Gastric Cancer

Hereditary Diffuse Gastric Cancer: British Columbia Cancer Agency Research Update June 2009

Posted by Karen Chelcun Schreiber On June - 22 - 2009

Current Research Projects of the Hereditary Diffuse Gastric Cancer Research Team at the British Columbia Cancer Agency.

David Huntsman, Pardeep Kaurah
 

Over the last 10 years, we have learnt a lot about hereditary diffuse gastric cancer (HDGC). However, there are still many critical knowledge deficits which need to be addressed to improve the cancer control of families with known CDH1 mutations and to inform the care of families with strong histories of gastric cancer of whom known mutations have been identified.

 

Our research team is both collaborating with other members of the International Gastric Cancer Linkage Consortium (IGCLC) to develop a more accurate understanding of the cancer risks associated with carrying CDH1 mutations, and is performing research locally that should help our global research community move forward.

 

Studies we are actively engaged in include: Read the rest of this entry »

Front, HDGC, Hereditary Diffuse Gastric Cancer, Research

TV New Zealand Close Up: The Kiwis who inspired a Grey’s plot

Posted by Karen Chelcun Schreiber On June - 14 - 2009

View an uplifting and interesting Close Up news broadcast about Hereditary Diffuse Gastric Cancer (HDGC) on TV New Zealand featuring Parry Guilford, the scientist who first identified HDGC and the CDH1 gene mutation that causes HDGC.  His discovery, only eleven years new, has been saving so many lives, including in the Chelcun family and many other families worldwide.  The Close Up includes interviews with the original families in whom HDGC was first identified.  We must find ways to fund the promising research that will ultimately lead to the prevention of this particular cancer as well as other related cancers.

Families, Fundraising, Genetics, HDGC, Hereditary Diffuse Gastric Cancer, News, Research

Hereditary Diffuse Gastric Cancer (HDGC): A Resource for You

Posted by Karen Chelcun Schreiber On June - 13 - 2009

HDGC...Now What?

Be sure to visit HDGC…Now What?

 

You, or someone close to you has been diagnosed with HDGC.  Now what?  The search is on, for information, for support, for encouragement.

  
We are committed to developing this network, a valuable source of credible and useful information.  Join our community of support for all of those touched by HDGC or other types of stomach cancer.  Your participation can be as little or as much as you desire.  You decide. Read the rest of this entry »

Education, Families, Fundraising, Gastrectomy, General, Genetics, Get Involved, HDGC, Hereditary Diffuse Gastric Cancer, Lobular Breast Cancer, Mind, Body, Spirit, News, Nutrition, Pregnancy, Research

Cancer Genetics Group in Portugal: Focus on the genetics of gastric, breast, and colorectal carcinoma

Posted by Karen Chelcun Schreiber On May - 22 - 2009

Group name/Designation:

Cancer Genetics

 

Group Leader:

Raquel Seruca

Principal Investigators related to gastric cancer research:
Carla Oliveira ( HDGC molecular genetics),
Fátima Carneiro ( Molecular Pathology),
Gianpaolo Suriano and Jose Carlos Machado ( Gastric cancer related signalling pathways)
Céu Figueiredo (Helicobacter pylori related research)

 

Principal Investigators related to breast cancer research:
Joana Paredes (Signalling pathways related to breast cancer invasion), 
Fernando Schmitt ( Molecular pathology),

Location of the Group (Host- Institution):

 IPATIMUP, Porto, Portugal

  

General Objectives of the Group

The research of our group focuses on the genetics of three common types of epithelial cancer: gastric, breast, and colorectal carcinoma. We focus at identifying 1) germline genetic alterations (high and low penetrance genes) associated with increased risk of these tumours; 2) pathological features and somatic molecular markers occurring in the setting of hereditary and sporadic carcinomas; 3) signalling pathways mediated by genetic and gene-environmental factors in tumour development in order to find molecular targets for therapeutic intervention. Read the rest of this entry »

Front, HDGC, Hereditary Diffuse Gastric Cancer, Lobular Breast Cancer, Research
  • Subscribe to News & Updates

  • Welcome

    Join the Be Strong Hearted Network

    Support one another through individual connections and group participation. Create your own journal/blog to share your story with others.

    Create Account

  • Tag Cloud

  • Archives

  • Who's Online

    There are no users currently online.

  • Members

  • Groups

  • Site Wide Activity

    • J Wielgoszinski updated the “Basic” information on their profile   3 days, 15 hours ago

    • J Wielgoszinski updated the “Cancer Profile” information on their profile   3 days, 15 hours ago

    • J Wielgoszinski updated the “Bio” information on their profile   3 days, 15 hours ago

    • Karen Chelcun Schreiber wrote a new blog post: Scientific Advisory Board   3 days, 21 hours ago

      Scientific Advisory Board members are highly accomplished professionals with medical and/or research background, who provide expert and comprehensive perspectives as well as guidance to No Stomach For Cancer, Inc. with regard to technical, medical, and research related topics. The Board provides knowledge and support that are critical in furthering our Mission.

      Daniel C. Chung, MD
      Massachusetts General [...]

    • Nina healey wrote on the wire of the group Lobular Breast Cancer   1 week, 1 day ago

      I am new to this group. I am actually a cousin of Lorraine Ennis. In March 2007, I was diagnosed with Invasive Lobular Carcinoma in my right breast. I had a mastectomy in March, during which the dr checked the lymph nodes by removing the main node and checked it while I [...]

    • Nina healey joined the group Lobular Breast Cancer   1 week, 1 day ago

    • Gretchen Borzi wrote on the wire of the group Lobular Breast Cancer   3 weeks, 2 days ago

      Lorraine and Cathy, you’re stories are inspiring. I wish you both the best of luck with your surgeries and recovery. Right now, it’s hard for me to imagine being in your shoes, but I will most likely be there at some point. Thanks for sharing.