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An article published recently in the Journal of Medical Genetics outlines new recommendations for management of patients and families with Hereditary Diffuse Gastric Cancer, based on a workshop of the International Gastric Cancer Linkage Consortium (IGCLC) held in late 2008.  The workshop, convened in Cambridge, UK, included expert geneticists, gastroenterologists, oncologists, surgeons, and pathologists from nine countries, and discussion topics included genetic counselling and testing, surveillance endoscopy, prophylactic gastrectomy, and review of pathology specimens.

Some of the outcomes of the IGCLC workshop include: Read the rest of this entry »

TV New Zealand Close Up: The Kiwis who inspired a Grey’s plot

Posted by Karen Chelcun Schreiber On June - 14 - 2009

View an uplifting and interesting Close Up news broadcast about Hereditary Diffuse Gastric Cancer (HDGC) on TV New Zealand featuring Parry Guilford, the scientist who first identified HDGC and the CDH1 gene mutation that causes HDGC.  His discovery, only eleven years new, has been saving so many lives, including in the Chelcun family and many other families worldwide.  The Close Up includes interviews with the original families in whom HDGC was first identified.  We must find ways to fund the promising research that will ultimately lead to the prevention of this particular cancer as well as other related cancers.

Hereditary Diffuse Gastric Cancer (HDGC): A Resource for You

Posted by Karen Chelcun Schreiber On June - 13 - 2009

HDGC...Now What?

Be sure to visit HDGC…Now What?

 

You, or someone close to you has been diagnosed with HDGC.  Now what?  The search is on, for information, for support, for encouragement.

  
We are committed to developing this network, a valuable source of credible and useful information.  Join our community of support for all of those touched by HDGC or other types of stomach cancer.  Your participation can be as little or as much as you desire.  You decide. Read the rest of this entry »

Pay Attention to the Pathologist Behind the Curtain

Posted by Karen Chelcun Schreiber On June - 10 - 2009

“You have doctors you’ve never met, but who are absolutely essential to your care. Pathologists are in the background, but are key to diagnosis, treatment and care,” says Kent B. Lewandrowski, MD, associate chief of Pathology and director of clinical services for the Pathology Department at Massachusetts General Hospital.

I personally discovered the critical nature of pathology in the treatment of HDGC while researching the topic after testing positive for the CDH1 gene mutation that causes HDGC. While interviewing a prospective surgeon I asked “Who will be analyzing my stomach, who is the pathologist?” This is how I first learned of Dr. Gregory Lauwers, his expertise with gastric cancer, his experience with HDGC patients, and more about the extensive and time consuming analysis that would be performed on my stomach following its removal. I met with Dr. Lauwers, approximately sixteen days following my surgery, to get my pathology results first hand and learn more about the process.  My stomach remains, in Boston, in wax blocks, in 170 sections, in a drawer, for all of eternity.  Read more about the importance of surgical pathology.

 

Pay Attention to the Pathologist Behind the Curtain, by Cathryn Delude

Massachusetts General Hospital, Cancer Center
Synergy, Winter/Spring 2009

Related Article:   Choosing a Surgeon: Ten questions to ask

You’re Having WHAT? About Total Gastrectomy

Posted by Karen Chelcun Schreiber On March - 2 - 2009

Prophylactic Total Gastrectomy (Preventive Complete Removal of Stomach)

Hereditary Diffuse Gastric Cancer (HDGC) is the type of gastric cancer caused by a mutation in the CDH1 gene. Because it is nearly impossible to detect at an early stage, the recommended procedure to prevent the development of this cancer in CDH1 gene mutation carriers is prophylactic total gastrectomy. The reconstruction is referred to as a Roux-en-y.

The Surgery

The diagrams below show the anatomy before and after reconstruction. Read the rest of this entry »

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      Scientific Advisory Board members are highly accomplished professionals with medical and/or research background, who provide expert and comprehensive perspectives as well as guidance to No Stomach For Cancer, Inc. with regard to technical, medical, and research related topics. The Board provides knowledge and support that are critical in furthering our Mission.

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      I am new to this group. I am actually a cousin of Lorraine Ennis. In March 2007, I was diagnosed with Invasive Lobular Carcinoma in my right breast. I had a mastectomy in March, during which the dr checked the lymph nodes by removing the main node and checked it while I [...]

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      Lorraine and Cathy, you’re stories are inspiring. I wish you both the best of luck with your surgeries and recovery. Right now, it’s hard for me to imagine being in your shoes, but I will most likely be there at some point. Thanks for sharing.