An article published recently in the Journal of Medical Genetics outlines new recommendations for management of patients and families with Hereditary Diffuse Gastric Cancer, based on a workshop of the International Gastric Cancer Linkage Consortium (IGCLC) held in late 2008. The workshop, convened in Cambridge, UK, included expert geneticists, gastroenterologists, oncologists, surgeons, and pathologists from nine countries, and discussion topics included genetic counselling and testing, surveillance... more
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The Doctors TV aired a program on Monday, February 1 titled Desperate To Save A Life. It includes a segment about Hereditary Diffuse Gastric Cancer (HDGC). If only one at risk family is identified, if only one life saved … View the two part segment: Desperate To Save A Life, Part One Desperate To Save A Life, Part Two Read More →
The possibility of having a healthy pregnancy and maintaining one’s own health is an issue that comes up again and again for young women who are affected by Hereditary Diffuse Gastric Cancer (HDGC) and are contemplating prophylactic total gastrectomy. Pardeep Kaurah provides the following report titled “Pregnancy after prophylactic total gastrectomy,” which was just published in January, 2010. Pregnancy after prophylactic total gastrectomy Read More →
The following is an excerpt from the as yet unpublished Cambridge meeting. The paper has just been accepted by the Journal of Medical Genetics and will be published early in the new year. “There is also emerging evidence for an increased risk of colon cancer in HDGC families, and these colon cancers can display signet ring cell features (personal communications David Huntsman and Paul Pharoah). In CDH1 families in which colon cancer is reported information should be collected concerning the... more
Gastric cancer is the second most common cause of cancer-related death in the world. The American Cancer Society estimated that 21,500 new cases of stomach (gastric) cancer would be diagnosed in the United States in 2008.1 Because gastric cancer is difficult to diagnose, it is often discovered in patients at a late stage with a poor prognosis. The treatment for gastric cancer is surgery and chemotherapy;2 however, the overall 5-year survival rate is low, at 24.3%.1 It is estimated that 1-3% of cases... more
WORKING TO RAISE AWARENESS CHELCUN FAMILY MEMBERS APPEAR IN CBS SEGMENT ABOUT HDGC The Chelcun family was featured in a CBS video segment with the goal of raising awareness of Hereditary Diffuse Gastric Cancer syndrome (HDGC). While it appears to be a story about the Chelcun family, the underlying story is that of families all throughout the world. Change the family name, the family size, the individuals, the city, the country, but the story remains the same. You may view the video, titled Surviving... more
“Top Medical Advances of the Decade” include mapping the human genome; CDH1 gene mutation is example
Watch the video about Mapping the Human Genome and Stomach Cancer. “Good Morning America” considers the discovery of genetic markers such as the one causing HDGC to be one of the top medical advances of the decade. Stomach cancer is mentioned specifically in this video from December 29, 2009 featuring Dr. Tim Johnson’s descriptions of medical breakthroughs. We are confident that the efforts of all of us impacted by HDGC and other diffuse gastric cancers, have already resulted in... more
A prestigious James Cook Fellowship has been awarded to researcher Parry Guilford, University of Otazo, New Zealand, to pursue innovative research aimed at reversing or preventing the very early stages of stomach cancer. Read Parry Guilford’s personal post detailing his exciting research plan for HDGC / CDH1 gene research. His two year fellowship will begin in March, 2010. The University of Otago announces Parry Guilford’s exciting award for stomach cancer research. More... more
No Stomach For Cancer
No Stomach For Cancer, Inc. is a charitable organization whose mission is to expedite education and research for early diagnosis, screening, treatment and prevention of Hereditary Diffuse Gastric Cancer (HDGC) and other diffuse gastric cancers and their related health risks, and to provide a network of support for affected families. Read more about HDGC on the Gastric Cancer page of this website.