The possibility of having a healthy pregnancy and maintaining one’s own health is an issue that comes up again and again for young women who are affected by Hereditary Diffuse Gastric Cancer (HDGC) and are contemplating prophylactic total gastrectomy. Pardeep Kaurah provides the following report titled “Pregnancy after prophylactic total gastrectomy,” which was just published in January, 2010. Pregnancy after prophylactic total gastrectomy Read More →
No Stomach For Cancer, Inc. has internal mechanisms in place to review the medical/scientific information provided on this site for accuracy, utilizing a network of medical and scientific advisors. Read More →
The following is an excerpt from the as yet unpublished Cambridge meeting. The paper has just been accepted by the Journal of Medical Genetics and will be published early in the new year. “There is also emerging evidence for an increased risk of colon cancer in HDGC families, and these colon cancers can display signet ring cell features (personal communications David Huntsman and Paul Pharoah). In CDH1 families in which colon cancer is reported information should be collected concerning the... more
Gastric cancer is the second most common cause of cancer-related death in the world. The American Cancer Society estimated that 21,500 new cases of stomach (gastric) cancer would be diagnosed in the United States in 2008.1 Because gastric cancer is difficult to diagnose, it is often discovered in patients at a late stage with a poor prognosis. The treatment for gastric cancer is surgery and chemotherapy;2 however, the overall 5-year survival rate is low, at 24.3%.1 It is estimated that 1-3% of cases... more
“Top Medical Advances of the Decade” include mapping the human genome; CDH1 gene mutation is example
Watch the video about Mapping the Human Genome and Stomach Cancer. “Good Morning America” considers the discovery of genetic markers such as the one causing HDGC to be one of the top medical advances of the decade. Stomach cancer is mentioned specifically in this video from December 29, 2009 featuring Dr. Tim Johnson’s descriptions of medical breakthroughs. We are confident that the efforts of all of us impacted by HDGC and other diffuse gastric cancers, have already resulted in... more
A prestigious James Cook Fellowship has been awarded to researcher Parry Guilford, University of Otazo, New Zealand, to pursue innovative research aimed at reversing or preventing the very early stages of stomach cancer. Read Parry Guilford’s personal post detailing his exciting research plan for HDGC / CDH1 gene research. His two year fellowship will begin in March, 2010. The University of Otago announces Parry Guilford’s exciting award for stomach cancer research. More... more
Parry Guilford; Cancer Genetics Laboratory, University of Otago The James Cook Fellowship provides funding for two years of concentrated research, free of teaching and administrative commitments. My planned research is built broadly around establishing methods to assess individual risk of developing gastric cancer. As we all know, CDH1 mutation carriers have a lifetime risk of around 70-80% of developing diffuse gastric cancer, but we have little understanding of an individual’s actual... more
CDH1 Mutations and Inheritance By Amy Stettner, MS, CGC Genetic Counselor Madison, WI Our bodies are made up of trillions of tiny cells. We have skin cells, muscle cells, bone cells, stomach cells, etc. Each cell contains a copy of our genetic code. This genetic code is made up of DNA and is packaged into structures called chromosomes. more Read More →
The Chelcun Family Fund for Stomach Cancer Research has accomplished much, in a very short time. Our website is a leading resource (if not the leading resource) for information about HDGC and support for HDGC families worldwide. We are writing to bring you up to date on what’s been happening, and to announce a major step forward. Our website at www.BeStrongHearted.org took off in a way none of us had anticipated. The statistics are astounding: visitors from 81 countries and every state in the... more
No Stomach For Cancer
No Stomach For Cancer, Inc. is a charitable organization whose mission is to expedite education and research for early diagnosis, screening, treatment and prevention of Hereditary Diffuse Gastric Cancer (HDGC) and other diffuse gastric cancers and their related health risks, and to provide a network of support for affected families. Read more about HDGC on the Gastric Cancer page of this website.